[ASC-list] Free ANZAAS talk, Melbourne, Wed 21st August 6:30 pm - "Clot busting enzymes, ischaemic stroke and vampire bats"

David Vaux D.Vaux at latrobe.edu.au
Tue Aug 13 07:05:47 UTC 2013

Free, all welcome (booking not needed) Bring your friends!

Free pizza and drinks after the talk

At GTAC, located in the grounds of University High School, corner Royal Parade and Story Street, Parkville (enter off Story Street or Royal Parade)

Wednesday 21st August 2013, 6:30 pm

Professor Rob Medcalf

School of Chemistry, University of Melbourne

"Clot busting enzymes, ischaemic stroke and vampire bats"

How do we remove blood clots? This is achieved by an enzyme called tissue type plasminogen activator (t-PA). In the mid-nineties, t-PA was approved for use in patients with ischaemic stroke, but only could be administered within a limited time period of 3 hours after stroke onset. t-PA has now been shown to play a number of important and surprising roles in the brain itself. Newer clot busting drugs are now being trialled in stroke patients to safely extend the current time frame for treatment. One of these drugs is a t-PA-like molecule derived from the saliva of the common vampire bat that appears to be the most selective clot busting enzyme known.

Professor Medcalf has investigated the role of the plasminogen activating system and fibrinolysis in Melbourne and in Lausanne, Switzerland. He was awarded the Monash University Faculty of Medicine "Silver Jubilee Prize for Medical Research" in 2003 and the 2005 Vice Chancellor's Award for Student Supervision" (Special Commendation). He was elected as Chairman of the International Society on Fibrinolysis and Proteolysis in 2004 and again in 2006.

*****Prof Medcalf’s talk will be preceded by a short talk by*****:

Dr. Anna Price

from The Murdoch Children's Research Institute Public Health Research Team

Forthcoming talk:

September 18th  Prof Ingrid Scheffer, Genetics of Epilepsy, Austin Health and RCH

We are pleased to acknowledge the support by CSL and GTAC for the ANZAAS Melbourne science talks series

Further Info:         David Vaux       9345 2941                davidlaurencevaux at gmail.com<mailto:davidlaurencevaux at gmail.com>

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